H-HoArg-OH-d4

H-HoArg-OH-d4 is a deuterium labeled H-HoArg-OH (HY-W008385) . H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

Product Specifications

CAS Number

[1332075-41-8]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

OC([C@@H](N)CC([2H])([2H])C([2H])([2H])CNC(N)=N)=O

Molecular Formula

C7H12D4N4O2

Molecular Weight

192.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Fishman W, et al. L-homoarginine; an inhibitor of serum "bone and liver" alkaline phosphatase. Clin Chim Acta. 1970 Aug;29 (2) :339-41.|[2]Atzler D, et al. L-homoarginine and cardiovascular disease. Curr Opin Clin Nutr Metab Care. 2015 Jan;18 (1) :83-8.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-246.