H-HoArg-OH-d4
H-HoArg-OH-d4 is a deuterium labeled H-HoArg-OH (HY-W008385) . H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.
Product Specifications
CAS Number
[1332075-41-8]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
OC([C@@H](N)CC([2H])([2H])C([2H])([2H])CNC(N)=N)=O
Molecular Formula
C7H12D4N4O2
Molecular Weight
192.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Fishman W, et al. L-homoarginine; an inhibitor of serum "bone and liver" alkaline phosphatase. Clin Chim Acta. 1970 Aug;29 (2) :339-41.|[2]Atzler D, et al. L-homoarginine and cardiovascular disease. Curr Opin Clin Nutr Metab Care. 2015 Jan;18 (1) :83-8.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-246.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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