Ingenol 3-monobenzoate
Product Specifications
UNSPSC Description
Ingenol 3-monobenzoate (Ingenol 3-benzoate) is a disgust inducing agent. Ingenol 3-monobenzoate can bind to and activate PKC (Ki=0.14 nM), inhibit the gene expression of phosphoenolpyruvate carboxykinase, thereby inhibiting gluconeogenesis, and increasing blood cortisol levels, producing food aversion[1].
Target Antigen
PKC
Type
Natural Products
Related Pathways
Epigenetics;TGF-beta/Smad
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ingenol-3-monobenzoate.html
Smiles
O[C@@]12[C@]3(C=C([C@@H]2OC(C4=CC=CC=C4)=O)C)C([C@](C=C([C@H]1O)CO)([H])[C@@]5([H])[C@@](C5(C)C)([H])C[C@H]3C)=O
Molecular Weight
452.54
References & Citations
[1]Kronberg, et al. "Potential aversive compounds in leafy spurge for ruminants and rats." Journal of chemical ecology 21 (1995): 1387-1399.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N13191/Ingenol-3-monobenzoate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N13191/
Clinical Information
No Development Reported
CAS Number
83036-64-0
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