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Nodularin

Nodularin is a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor[1].

Product Specifications

CAS Number

[118399-22-7]

UNSPSC

12352209

Hazard Statement

H300+H310+H330-H315-H317-H319-H335

Target

Phosphatase

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nodularin.html

Solubility

10 mM in DMSO

Smiles

CC(/C=C/[C@@H]([C@@H](C(N[C@H](CCC(N(/C1=C\C)C)=O)C(O)=O)=O)C)NC([C@@H](NC([C@H]([C@@H](NC1=O)C(O)=O)C)=O)CCCNC(N)=N)=O)=C\[C@H](C)[C@@H](OC)CC2=CC=CC=C2

Molecular Formula

C41H60N8O10

Molecular Weight

824.96

Precautions

P260-P261-P262-P264-P270-P271-P272-P280-P284-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501

References & Citations

[1]Namikoshi, et al. New Nodularins: A General Method for Structure Assignment. The Journal of Organic Chemistry. 1994, 59 (9), 2349–2357.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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