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TLE3 rabbit pAb

This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013],

Product Specifications

Background

This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]

Product Name Alternative

Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)

UniProt

Q04726

Swiss Prot

Q04726

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human TLE3 AA range: 257-307

Target

TLE3

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Molecular Weight

85kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

85kD

Fragment

IgG

Subcellular Location

Nucleus.

Other Product Names

Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)

Gene ID (Human)

7090

Available Sizes

Curated Selection

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