CGP 25454A
CGP 25454A is a selective presynaptic dopamine autoreceptor antagonist which induces the increase of dopamine and acetyl choline. CGP 25454A can be used for major depression research[1].
Product Specifications
CAS Number
[104391-26-6]
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/CGP-25454A.html
Purity
99.65
Solubility
DMSO : ≥ 3.5 mg/mL
Smiles
O=C(NCCN(CC)CC)C1=CC(C#N)=C(Cl)C=C1OC.[H]Cl
Molecular Formula
C15H21Cl2N3O2
Molecular Weight
346.25
References & Citations
[1]Bischoff S et al. CGP 25454A, a novel and selective presynaptic dopamine autoreceptor antagonist.
 Naunyn Schmiedebergs Arch Pharmacol. 1994 Sep;350 (3) :230-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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