Rovalpituzumab

Rovalpituzumab is a humanized monoclonal antibody against delta-like protein 3 (DLL3) . Rovalpituzumab can be used in the synthesis of antibody-drug conjugate (ADC), Rovalpituzumab Tesirine. Rovalpituzumab has activity against small cell lung cancer (SCLC) [1].

Product Specifications

CAS Number

[1613313-01-1]

Product Name Alternative

SC-0001

UNSPSC

12352203

Target

Notch

Type

Inhibitory Antibodies

Related Pathways

Neuronal Signaling; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rovalpituzumab.html

Purity

99.84

Solubility

H2O

Smiles

[Rovalpituzumab]

Molecular Weight

(145.02 kDa)

References & Citations

[1]Bilal H Lashari, et al. Rovalpituzumab Tesirine: A Novel DLL3-Targeting Antibody-Drug Conjugate. Drugs R D. 2018 Dec;18 (4) :255-258.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Available Sizes

Curated Selection

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