Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Sematilide (hydrochloride)

Sematilide hydrochloride (CK-1752 hydrochloride) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM) . Sematilide is a class III antiarrhythmic agent[1].

Product Specifications

CAS Number

[101526-62-9]

Product Name Alternative

CK-1752 (hydrochloride)

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sematilide-hydrochloride.html

Purity

99.33

Solubility

DMSO : 1.67 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NCCN(CC)CC)C1=CC=C(NS(=O)(C)=O)C=C1.Cl

Molecular Formula

C14H24ClN3O3S

Molecular Weight

349.88

References & Citations

[1]Ishii Y, et al. Effects of Sematilide, a novel class III antiarrhythmic agent, on membrane currents in rabbit atrial myocytes. Eur J Pharmacol. 1997 Jul 23;331 (2-3) :295-302.|[2]Stanley S. Greenberg, et al. Pharmacology of Sematilide, a non-quaternary class III antiarrhythmic agent.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human NEUROD4 activation kit by CRISPRa
GA111755 1 Kit

Human NEUROD4 activation kit by CRISPRa

Ask
View Details
Gastrin (1-17) -BSA
MF-0108810-01 10 mg

Gastrin (1-17) -BSA

Ask
View Details
Gastrin (1-17) -BSA
MF-0108810-02 5 mg

Gastrin (1-17) -BSA

Ask
View Details
Gastrin (1-17) -BSA
MF-0108810-03 1 mg

Gastrin (1-17) -BSA

Ask
View Details
GENLISA Rat Alpha 2-Antiplasmin (a2PI) ELISA
KLR2585 1x 96 Well

GENLISA Rat Alpha 2-Antiplasmin (a2PI) ELISA

Ask
View Details
Caveolin 1 (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22kD, Cell Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21) (MaxLight 650) discontinued
C2097-91T-ML650 100 µL

Caveolin 1 (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22kD, Cell Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21) (MaxLight 650) discontinued

Ask
View Details