CRBN ligand-11
Product Specifications
UNSPSC Description
CRBN ligand-11 is the E3 ubiquitin ligase ligand for CFT8634 (HY-145925B). CRBN ligand-11 can be used for the synthesis of PROTACs[1][2].
Target Antigen
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/crbn-ligand-11.html
Smiles
O=C(C(NC1=CC=C(Br)C(F)=C1)CC2)NC2=O
Molecular Weight
301.11
References & Citations
[1]Zhang xue, et al. Nitrogen-containing heteroaromatic ring compound as well as composition and pharmaceutical use thereof. Patent, WO2023143370, 2023-08-03.|[2]Nasveschuk CG, et, al. Compounds for targeted degradation of brd9. Patent, WO2021178920A1, 2021-09-10.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169989/CRBN-ligand-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169989/
Clinical Information
No Development Reported
CAS Number
2962967-27-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
