DB28

DB28 is a novel MR1 ligand. DB28 decreases cell surface expression of MR1 and competitively inhibits activation of MAIT cells by agonist ligands[1].

Product Specifications

CAS Number

[16296-42-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

MHC

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/db28.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CCNC(C(NC1=O)=CC(N1)=O)=O

Molecular Formula

C8H9N3O5

Molecular Weight

227.17

Precautions

H315, H319, H335

References & Citations

[1]Alexandra J Corbett, et al. Antigen Recognition by MR1-Reactive T Cells; MAIT Cells, Metabolites, and Remaining Mysteries. Front Immunol. 2020 Aug 27:11:1961.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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