CDK7 ligand 2

CDK7 ligand 2 (Compound A6) is a CDK7 ligand. CDK7 ligand 2 can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2603381-71-9]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk7-ligand-2.html

Purity

99.92

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NC1=NNC2=C1CN(C(N[C@@H](C3=CC=CC=C3)CN(C)C)=O)C2(C)C)C4=CC=C(C(O)=O)C=C4

Molecular Formula

C26H30N6O4

Molecular Weight

490.55

References & Citations

[1]Wenzhi Ji, et al. Discovery of Bivalent Small Molecule Degraders of Cyclin-dependent Kinase 7 (CDK7) . European Journal of Medicinal Chemistry (2024) : 116613.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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