CDK7 ligand 2
CDK7 ligand 2 (Compound A6) is a CDK7 ligand. CDK7 ligand 2 can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2603381-71-9]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk7-ligand-2.html
Purity
99.92
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NC1=NNC2=C1CN(C(N[C@@H](C3=CC=CC=C3)CN(C)C)=O)C2(C)C)C4=CC=C(C(O)=O)C=C4
Molecular Formula
C26H30N6O4
Molecular Weight
490.55
References & Citations
[1]Wenzhi Ji, et al. Discovery of Bivalent Small Molecule Degraders of Cyclin-dependent Kinase 7 (CDK7) . European Journal of Medicinal Chemistry (2024) : 116613.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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