N-Butyl-N-(4-hydroxybutyl)nitrosamine
Product Specifications
UNSPSC Description
N-Butyl-N-(4-hydroxybutyl)nitrosamine is a potent mutagen that can cause high-level of mutagenesis specifically in the epithelial cells (urothelial) of the urinary bladder. N-Butyl-N-(4-hydroxybutyl)nitrosamine is used to induce bladder cancer in rodents[1].
Target Antigen
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-butyl-n-4-hydroxybutyl-nitrosamine.html
Purity
99.68
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
CCCCN(N=O)CCCCO
Molecular Weight
174.24
References & Citations
[1]Zhiming He, et al. Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesis. Mutat Res. 2012 Feb 18;742(1-2):92-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W755252/N-Butyl-N-4-hydroxybutyl-nitrosamine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W755252/N-Butyl-N-4-hydroxybutyl-nitrosamine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3817-11-6
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