Fenchlorphos
Fenchlorphos, an organophosphate, is an insecticide. Fenchlorphos is an inhibitor of the enzyme acetylcholinesterase (AChE) . Fenchlorphos is able to cause mitochondrial dysfunction[1][2].
Product Specifications
CAS Number
[299-84-3]
UNSPSC
12352005
Hazard Statement
H302+H312, H410
Target
Cholinesterase (ChE) ; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Fenchlorphos.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
S=P(OC)(OC)OC1=CC(Cl)=C(Cl)C=C1Cl
Molecular Formula
C8H8Cl3O3PS
Molecular Weight
321.55
Precautions
H302+H312, H410
References & Citations
[1]Nafstad I, et, al. Teratogenic effects of the organophosphorus compound fenchlorphos in rabbits. Acta Vet Scand. 1983;24 (3) :295-304.|[2]Rimkus SA, et, al. A pharmacological screen for compounds that rescue the developmental lethality of a Drosophila ATM mutant. PLoS One. 2018 Jan 16;13 (1) :e0190821.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
Available Sizes
Curated Selection
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