Napamezole
Product Specifications
UNSPSC Description
Napamezole is an α2A adrenergic receptor antagonist and a serotonin/norepinephrine uptake inhibitor. Napamezole increases the levels of monoamines in the brain by blocking monoamine uptake, which gives it antidepressant activity[1].
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/napamezole.html
Smiles
C1(CC2=NCCN2)=CC3=CC=CC=C3CC1
Molecular Weight
212.29
References & Citations
[1]Cordi AA, et al. Potential antidepressants displayed combined alpha(2)-adrenoceptor antagonist and monoamine uptake inhibitor properties. J Med Chem. 2001 Mar 1;44(5):787-805.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105699/Napamezole-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105699/
Clinical Information
Phase 3
CAS Number
91524-14-0
Curated Selection
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