KM91104
KM91104, a cell-permeable V-ATPase inhibitor, specifically targets the a3-b2 subunits of V-ATPase[1].
Product Specifications
CAS Number
[304481-60-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Proton Pump
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/km91104.html
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 5 mg/mL (ultrasonic)
Smiles
O=C(N/N=C/C1=CC=CC=C1O)C2=CC=C(O)C(O)=C2
Molecular Formula
C14H12N2O4
Molecular Weight
272.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Marrone G, et al. The adenosine monophosphate-activated protein kinase-vacuolar adenosine triphosphatase-pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells. Hepatology. 2018;68 (3) :1140-1153. |[2]Göttle P, et al. Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination. Glia. 2019;67 (1) :160-170. doi:10.1002/glia.23535
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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