CS587

CS587 is a specific inhibitor of CaMK1D with neurocytotoxicity at 10 μM. CS587 modulates the sensitivity of neuronal cells to Aβ oligomer toxicity[1].

Product Specifications

CAS Number

[2388506-69-0]

UNSPSC

12352005

Target

CaMK

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cs587.html

Purity

98.18

Solubility

DMSO : 100 mg/mL (ultrasonic; warming)

Smiles

NC(C1=CN=C(N2C[C@H](CCC2)N)N=C1NC3=CC(C(C)(C)C#N)=CC(C(C)(C)C#N)=C3)=O

Molecular Formula

C24H30N8O

Molecular Weight

446.55

References & Citations

[1]Grant P, et al. Effects of Specific Inhibitors for CaMK1D on a Primary Neuron Model for Alzheimer's Disease. Molecules. 2021 Dec 18;26 (24) :7669.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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