AVE-9488
AVE-9488 is an eNOS enhancer with the activity of protecting the heart from ischemia-reperfusion injury. AVE-9488 can upregulate eNOS expression, increase NO production, reduce myocardial ischemia-reperfusion injury, and reduce the level of reactive oxygen species[1].
Product Specifications
CAS Number
[291756-32-6]
UNSPSC
12352005
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ave-9488.html
Purity
99.77
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1CC2=C(C=CC=C2)C1)C3=CC=C(F)C=C3
Molecular Formula
C16H14FNO
Molecular Weight
255.29
References & Citations
[1]The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ENOS
Available Sizes
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