α-Synuclein 4554W
α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinson’s disease[1].
Product Specifications
CAS Number
[2243207-00-1]
UNSPSC
12352209
Target
α-synuclein
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-synuclein-4554w.html
Purity
99.53
Solubility
H2O : ≥ 50 mg/mL
Smiles
Molecular Formula
C45H80N14O14
Molecular Weight
1041.20
References & Citations
[1]Torpey J H, et al. Insights into peptide inhibition of alpha-synuclein aggregation[J]. Frontiers in Neuroscience, 2020, 14: 561462.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation
Available Sizes
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