Daunomycinone (Standard)

Daunomycinone (Standard) is the analytical standard of Daunomycinone (HY-114658) . This product is intended for research and analytical applications. Daunomycinone (NSC-109351) is a metabolite of Daunomycin (HY-13062A) and anticancer intermediate. Daunomycinone binds to nucleic acids synergistically with metal ions. Daunomycinone can be used in the research of leukemia[1][2][3][4][5].

Product Specifications

CAS Number

[21794-55-8]

Product Name Alternative

NSC-109351 (Standard)

UNSPSC

12352005

Target

Drug Intermediate; Drug Metabolite; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/daunomycinone-standard.html

Smiles

O=C(C1=CC=CC(OC)=C1C2=O)C3=C2C(O)=C4[C@H](C[C@](C(C)=O)(CC4=C3O)O)O

Molecular Formula

C21H18O8

Molecular Weight

398.36

References & Citations

[1]Herman EH, et al. Modification of some of the toxic effects of daunomycin (NSC-82,151) by pretreatment with the antineoplastic agent ICRF 159 (NSC-129,943) . Toxicol Appl Pharmacol. 1974 Mar;27 (3) :517-26.|[2]Tan C, et al. Daunomycin, an antitumor antibiotic, in the treatment of neoplastic disease. Clinical evaluation with special reference to childhood leukemia. Cancer. 1967 Mar;20 (3) :333-53.