IMP-2373
Product Specifications
UNSPSC Description
IMP-2373 is the activity-based probe (ABP). IMP-2373 is a covalent pan- deubiquitinase(DUB) ABP to monitor DUB activity in physiologically relevant live cells[1].
Target Antigen
Deubiquitinase; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage;Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imp-2373.html
Solubility
10 mM in DMSO
Smiles
C#CC1=CC=C(CNC(C2=CC(C(C3CN(C#N)CC3)=O)=CN2C)=O)C=C1
Molecular Weight
360.41
References & Citations
[1]Daniel Conole, et al. Discovery of a Potent Deubiquitinase (DUB) Small-Molecule Activity-Based Probe Enables Broad Spectrum DUB Activity Profiling in Living Cells. Angew Chem Int Ed Engl. 2023, 62, 47.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D2188/IMP-2373-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D2188/
Clinical Information
No Development Reported
Curated Selection
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