Lactate
Product Specifications
UNSPSC Description
Lactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lactate.html
Purity
91.61
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
CC(O)C(O)=O
Molecular Weight
90.078
References & Citations
[1]Lucia Longhitano, et al. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype. Int J Mol Sci. 2022 Dec 20;24(1):24.|[2]Qiang Feng, et al. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nat Commun. 2022 Sep 6;13(1):4981. Adv Sci (Weinh). 2024 May 20:e2307216.|Bioact Mater. 2024 Jun 24:40:445-459.|Cancer Immunol Immunother. 2024 Oct 3;73(12):254.|J Ginseng Res. 2023 Dec 27.|Tissue Cell. 2024 Jul 9:89:102468.|Cell Res. 2023 Jul 13.|J Anim Sci Biotechnol. 2024 Jun 11;15(1):86.|J Exp Clin Cancer Res. 2024 Mar 5;43(1):68.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B2227/Lactate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B2227/Lactate-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
50-21-5
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7197214 Inquire
Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) TADA3 Polyclonal Antibody
Ask
View Details 