Compound C108

Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis[1][2].

Product Specifications

CAS Number

[15533-09-2]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/compound-c108.html

Concentration

10mM

Purity

99.32

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(N/N=C(C1=CC=CC=C1O)\C)C2=CC=CC=C2O

Molecular Formula

C15H14N2O3

Molecular Weight

270.28

Precautions

H315, H319

References & Citations

[1]Gupta N, et al. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017 Jan 31;114 (5) :1033-1038. |[2]Zheng Y, et al. G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript. Oncogene. 2022 Jan;41 (4) :515-526.