RVG

RVG (RVG29) is a peptide derived from Rabies Virus Glycoprotein that binds to the α-7 subunit of nicotinic acetylcholine receptors (AchR) of neuronal cells. RVG enhances delivery of Mycobacterium tuberculosis antigens to antigen-presenting cells[1].

Product Specifications

CAS Number

[115136-25-9]

Product Name Alternative

RVG29; RDP; Rabies Virus Glycoprotein-29

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/rvg.html

Purity

99.72

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

C([C@@H](C(N[C@H](C(=O)N1[C@H](C(N[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(=O)N3[C@H](C(NCC(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)CC(N)=O)=O)CO)=O)C)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)CCCNC(=N)N)=O)CO)=O)CC(N)=O)=O)[C@@H](C)O)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CS)=O)CCC4)[C@@H](C)O)=O)=O)CCC3)CCCNC(=N)N)=O)CCC2)CC(N)=O)=O)CCC(O)=O)=O)CCC1)CCSC)=O)NC([C@@H](NC([C@@H](NC([C@H](CC6=CC=C(O)C=C6)N)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)C=7C=8C(NC7)=CC=CC8

Molecular Formula

C141H217N43O43S2

Molecular Weight

3266.62

References & Citations

[1]Omar Garnica, et al. Enhanced delivery of Mycobacterium tuberculosis antigens to antigen presenting cells using RVG peptide. Tuberculosis (Edinb) . 2019 May:116S:S34-S41.