NSC 135130
NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates[1].
Product Specifications
CAS Number
[24164-06-5]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc-135130.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)[C@H](C(C)C)N(C(OC(C)(C)C)=O)C
Molecular Formula
C12H23NO4
Molecular Weight
245.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Malkov AV, Vranková K, Cerný M, Kocovský P. On the selective N-methylation of BOC-protected amino acids. J Org Chem. 2009 Nov 6;74 (21) :8425-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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