NSC80734
NSC80734 is a IL- 18 inhibitor. NSC80734 disrupts hIL-18 binding to the ectromelia virus IL-18BP. NSC80734 inhibits IL-18-induced production of IFN-γ[1].
Product Specifications
CAS Number
[501950-47-6]
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nsc80734.html
Purity
98.08
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=CC=C(NC(NC2=CC=C(C=C2)OC3=CC=C(NC(NC4=CC=C(C=C4)C#N)=O)C=C3)=O)C=C1
Molecular Formula
C28H20N6O3
Molecular Weight
488.50
References & Citations
[1]Krumm B, et al. Identification of small molecule inhibitors of Interleukin-18. Sci Rep. 2017 Mar 28;7 (1) :483.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
127716-ML550 100 µL
HAMP (Hepcidin, Liver-expressed Antimicrobial Peptide 1, LEAP-1, Putative Liver Tumor Regressor, PLTR, HEPC, LEAP1, UNQ487/PRO1003) (MaxLight 550)
Ask
View Details 
MBS1131313-01 0.02 mg (E-Coli)
Recombinant Mycobacterium marinum Glucose-1-phosphate adenylyltransferase (glgC)
Ask
View Details MBS1131313-02 0.02 mg (Yeast)
Recombinant Mycobacterium marinum Glucose-1-phosphate adenylyltransferase (glgC)
Ask
View Details