NSC80734

NSC80734 is a IL- 18 inhibitor. NSC80734 disrupts hIL-18 binding to the ectromelia virus IL-18BP. NSC80734 inhibits IL-18-induced production of IFN-γ[1].

Product Specifications

CAS Number

[501950-47-6]

UNSPSC

12352005

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nsc80734.html

Purity

98.08

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CC1=CC=C(NC(NC2=CC=C(C=C2)OC3=CC=C(NC(NC4=CC=C(C=C4)C#N)=O)C=C3)=O)C=C1

Molecular Formula

C28H20N6O3

Molecular Weight

488.50

References & Citations

[1]Krumm B, et al. Identification of small molecule inhibitors of Interleukin-18. Sci Rep. 2017 Mar 28;7 (1) :483.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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