Kojibiose

Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo[1][2].

Product Specifications

CAS Number

[2140-29-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/kojibiose.html

Purity

99.76

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](C=O)O[C@H]1-;@O-;@[C@@H](-;@[C@@H](O)-;@[C@H](O)-;@[C@H]-;@1O)CO

Molecular Formula

C12H22O11

Molecular Weight

342.30

Precautions

H302, H315, H319, H335

References & Citations

[1]José Moisés Laparra, et al. Kojibiose ameliorates arachidic acid-induced metabolic alterations in hyperglycaemic rats. Br J Nutr. 2015 Nov 14;114 (9) :1395-402.|[2]Miaomiao Wang, et al. Cloning and expression of the sucrose phosphorylase gene in Bacillus subtilis and synthesis of kojibiose using the recombinant enzyme. Microb Cell Fact. 2018 Feb 15;17 (1) :23.