Revdofilimab
Revdofilimab (ABBV-368) is a human IgG1 agonist monoclonal antibody against OX40. Among them, OX40 is a member of the TNF receptor superfamily expressed on activated and memory T cell subsets and T regulatory cells[1].
Product Specifications
CAS Number
[2230138-89-1]
Product Name Alternative
ABBV-368
UNSPSC
12352203
Target
Orexin Receptor (OX Receptor)
Type
Inhibitory Antibodies
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/revdofilimab.html
Purity
99.35
Solubility
10 mM in DMSO
Smiles
[Revdofilimab]
Molecular Weight
(145.62 kDa)
References & Citations
[1]A. Spira, et al. Safety, tolerability, and pharmacokinetics of the OX40 agonist ABBV-368 in patients with advanced solid tumors. ABSTRACTS IMMUNOTHERAPY OF CANCER| VOLUME 29, SUPPLEMENT 8, VIII409, OCTOBER 2018
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1
Available Sizes
Curated Selection
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