D- (-) -Quinic acid

D- (-) -Quinic acid scavenges hydrogen peroxide (IC50=87.11 μg/mL) and exhibits antioxidant activity. D- (-) -Quinic acid is the inhibitor for MAO and α-Glucosidase (IC50 =93.75 μg/mL) . D- (-) -Quinic acid is orally active[1][2].

Product Specifications

CAS Number

[77-95-2]

UNSPSC

12352211

Hazard Statement

H319

Target

Endogenous Metabolite; Glycosidase; Monoamine Oxidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/D-_-_-Quinic_acid.html

Purity

98.0

Solubility

H2O : 116.67 mg/mL (ultrasonic)

Smiles

O=C([C@]1(O)C[C@@H](O)[C@@H](O)[C@H](O)C1)O

Molecular Formula

C7H12O6

Molecular Weight

192.17

Precautions

H319

References & Citations

[1]Dong J, et al., Protective effect of D- (-) -quinic acid as food supplement in modulating AMP-activated protein kinase signalling pathway activation in HFD induced obesity. Hum Exp Toxicol. 2022 Jan-Dec;41:9603271221119804.|[2]Liu L, et al., Neuroprotective Effects of D- (-) -Quinic Acid on Aluminum Chloride-Induced Dementia in Rats. Evid Based Complement Alternat Med. 2020 May 11;2020:5602597.