2-Chlorobenzimidazole

2-Chlorobenzimidazole is a pharmaceutical intermediate used in the synthesis of a series of derivatives with anti-human cytomegalovirus (HCMV) activity. 2-Chlorobenzimidazole can be used to form metal complexes (cobalt, copper, and zinc), with zinc complexes exhibiting significant anticancer activity[1][2].

Product Specifications

CAS Number

[4857-06-1]

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Drug Intermediate

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-chlorobenzimidazole.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=NC2=CC=CC=C2N1

Molecular Formula

C7H5ClN2

Molecular Weight

152.58

Precautions

H315, H319, H335

References & Citations

[1]Zou R, Drach JC, Townsend LB. Design, synthesis, and antiviral evaluation of 2-chloro-5,6-dihalo-1-beta-D-ribofuranosylbenzimidazoles as potential agents for human cytomegalovirus infections. J Med Chem. 1997 Feb 28;40 (5) :811-8. |[2]Sánchez-Guadarrama O, et al. Cytotoxic activity, X-ray crystal structures and spectroscopic characterization of cobalt (II), copper (II) and zinc (II) coordination compounds with 2-substituted benzimidazoles. J Inorg Biochem. 2009 Sep;103 (9) :1204-13.