BRD4097
Product Specifications
UNSPSC Description
BRD4097 is an inhibitor of histone deacetylase (HDAC). BRD4097 acts by inhibiting the activity of HDACs, especially HDAC 1,2 and 3, through metal chelation and spatial rejection mechanisms, and this inhibition may help regulate gene expression and alter chromatin structure, thereby affecting a variety of biological processes. BRD4097 is used to study the role of HDAC in cholesterol metabolism and NPC1 diseases[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/brd4097.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(NC(C)=O)C=C1)NC2=CC=C(C)C=C2N
Molecular Weight
283.33
References & Citations
[1]Cruz D L, et al. Inhibition of histone deacetylases 1, 2, and 3 enhances clearance of cholesterol accumulation in Niemann-Pick C1 fibroblasts[J]. ACS Pharmacology & Translational Science, 2021, 4(3): 1136-1148.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121315/BRD4097-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121315/
Clinical Information
No Development Reported
CAS Number
1550053-19-4
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