BDZ-g

BDZ-g is a potent, selective antagonist of AMPA receptor. BDZ-g has the potential for the research of various neurological disorders involving excessive activity of AMPA receptors[1].

Product Specifications

CAS Number

[732278-52-3]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bdz-g.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CC(C=C(C=C1)C(C2=C(C3)C=C4C(OCO4)=C2)=NN(C(S5)=NN=C5C)[C@@H]3C)=C1N

Molecular Formula

C21H21N5O2S

Molecular Weight

407.49

References & Citations

[1]Wang C, et al. Mechanism and site of inhibition of AMPA receptors: pairing a thiadiazole with a 2,3-benzodiazepine scaffold. ACS Chem Neurosci. 2014;5 (2) :138-147.