SGC3027
SGC3027 is a histone methyltransferase inhibitor[1]. SGC3027 is the first potent, selective and cell active chemical probe for PRMT7[2].
Product Specifications
CAS Number
[2624313-13-7]
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SGC3027.html
Purity
98.06
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(C2=CC(CN(C(CC(C)(C)C3=C(C)C(C(C)=C(C)C3=O)=O)=O)CCCCSC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C(N=CN=C6N)=C6N=C5)O4)=CC=C2)C=C1
Molecular Formula
C41H47ClN6O6S
Molecular Weight
787.37
References & Citations
[1]Cermakova K, et al. Next-Generation Drugs and Probes for Chromatin Biology: From Targeted Protein Degradation to Phase Separation. Molecules. 2018 Aug 6;23 (8) . pii: E1958.|[2]SGC3027 for PRMT7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT7
Available Sizes
Curated Selection
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