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ARN25062

Product Specifications

UNSPSC Description

ARN25062 (compound 27) is a CDC42/RHOJ inhibitor with antitumor activity. ARN25062 is a novel trisubstituted pyrimidine derivative[1].

Target Antigen

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein;MAPK/ERK Pathway

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/arn25062.html

Smiles

FC(F)(C1=CC(NC2=CC(C3=CC=CC=C3)=NC(C4CCNCC4)=N2)=CC=C1)F

Molecular Weight

398.42

References & Citations

[1]Nicoletta Brindani, et al. Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer. J Med Chem. 2023 Apr 27;66(8):5981-6001.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-167828/ARN25062-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-167828/

Clinical Information

No Development Reported

CAS Number

3036492-85-7

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