Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His Tag (MALS verified)
Cynomolgus / Rhesus macaque BCMA, His Tag (BCA-C52H7) is expressed from human 293 cells (HEK293) . It contains AA Met 1 - Ala 53 (Accession # A0A2K5UD97-1) . In the region Met 1 - Ala 53, the AA sequence of Cynomolgus and Rhesus macaque BCMA are homologus.
Product Specifications
Background
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.9 kDa. The protein migrates as 13-14 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
A0A2K5UD97-1
Expression Region
Met 1 - Ala 53
Host
HEK293
Target
BCMA
Conjugation
Unconjugated
Tag
C-10xHis
Source
Cynomolgus / Rhesus macaque
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Cynomolgus / Rhesus macaque BCMA, His Tag (Cat. No. BCA-C52H7) at 2 μg/mL (100 μL/well) can bind Human BAFF, Fc Tag, active trimer (Cat. No. BAF-H5261) with a linear range of 0.2-3 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
7.9 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/BCA-C52H7.pdf
Species
Cynomolgus / Rhesus macaque
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