Aminopterin N-hydroxysuccinimide ester
Product Specifications
UNSPSC Description
Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible
Methotrexate (HY-14519) influx carrier inhibitor. Aminopterin N-hydroxysuccinimide ester can be used for the research of rheumatoid arthritis and a number of cancers (such as acute lymphoblastic leukemia)[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aminopterin-n-hydroxysuccinimide-ester.html
Smiles
NC1=NC(N)=NC2=C1N=C(CN(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C)C=N2.O=C4N(C(CC4)=O)O
Molecular Weight
569.53
References & Citations
[1]Henderson GB, et al. Characterization of the multiple transport routes for methotrexate in L1210 cells using phthalate as a model anion substrate. J Membr Biol. 1985;85(3):263-268. |[2]Chiao JH, et al. RFC-1 gene expression regulates folate absorption in mouse small intestine. J Biol Chem. 1997;272(17):11165-11170.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148657/Aminopterin-N-hydroxysuccinimide-ester-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148657/
Clinical Information
No Development Reported
CAS Number
98457-88-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Monoclonal CD38 Antibody (CD38/8335R) [Janelia Fluor 646]](https://cdn.genprice.uk/genprice/genprice4.png)
NBP3-24279JF646 0.1 mL
Rabbit Monoclonal CD38 Antibody (CD38/8335R) [Janelia Fluor 646]
Ask
View Details 