AI-4-57
Product Specifications
UNSPSC Description
AI-4-57 is an allosteric inhibitor for CBFβ SMMHC-RUNX1 interaction with an IC50 of 22 μM[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ai-4-57.html
Smiles
COC1=CC=C2N=C(C3=NC=CC=C3)NC2=C1
Molecular Weight
225.25
References & Citations
[1]Illendula A, et al., A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. Science. 2015 Feb 13;347(6223):779-84.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125966/AI-4-57-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125966/
Clinical Information
No Development Reported
CAS Number
63053-14-5
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