Gamma Synuclein Pre-formed Fibrils (Type 1)
Human Recombinant Gamma Synuclein Protein Pre-formed Fibrils (Type 1)
Product Specifications
Background
Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1). A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2). Its expression in breast tumors is also a marker for tumor progression (3).
Product Name Alternative
BCSG1 Aggregate Protein, Breast cancer specific gene 1 Aggregate Protein, Breast cancer specific Protein 1 Agreggates, Gamma-synuclein Aggregate Protein, Persyn Aggregate Protein, PRSN Aggregate Protein, SNCG Aggregate Protein, SR Aggregate Protein, Synoretin Aggregate Protein, Synuclein gamma Aggregate Protein, SYUG_HUMAN Aggregate Protein
UNSPSC
12352202
Gene ID
6623
Swiss Prot
O76070
Accession Number
NP_003078.2
Cellular Locus
Cytoskeleton | Centrosome | Spindle | Perinuclear Region
Host
E. coli
Origin Species
Human
Target
Gamma Synuclein
Conjugation
No tag
Applications
WB, SDS-PAGE, In vivo assay, In vitro assay
Purification Method
Ion-exchange Purified
Concentration
2 mg/ml
Purity
>95%
Weight
0.5
Length
Full length
Buffer
PBS pH 7.4
Molecular Weight
13.33 kDa
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.
Additionnal Information
For best results, sonicate immediately prior to use. Refer to the Neurodegenerative Protein Handling Instructions on our website, or the product datasheet for further information. Monomer source is catalog# SPR-407.
References & Citations
1. Nishioka K., et al. (2010) Arch Neurol. 67(8): 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88(9): 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26(1): 32-42.
Product MSDS
https://cdn.gentaur.com/products/400/4430714/msds/spr-459e.pdf
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