Gamma Synuclein Monomers

Human Recombinant Gamma Synuclein Monomers

Product Specifications

Background

Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1) . A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2) . Its expression in breast tumors is also a marker for tumor progression (3) .

Product Name Alternative

BCSG1 Protein Monomer, Breast cancer specific gene 1 Protein Monomer, Breast cancer specific Protein 1 Monomer, Gamma-synuclein Protein Monomer, Persyn Protein Monomer, PRSN Protein Monomer, SNCG Protein Monomer, SR Protein Monomer, Synoretin Protein Monomer, Synuclein gamma Protein Monomer, SYUG_HUMAN Protein Monomer

UNSPSC

12352202

UN Code

Non-hazardous

Hazard Statement

Non-hazardous

Gene ID

6623

Swiss Prot

O76070

Accession Number

NP_003078.2

Cellular Locus

Cytoskeleton | Centrosome | Spindle | Perinuclear Region

Expression System

E. coli

Host

E. coli

Origin Species

Human

Target

Gamma Synuclein

Conjugation

No tag

Nature

Recombinant

Applications

WB | SDS-PAGE | In vivo assay | In vitro assay

Field of Research

Purification Method

Ion-exchange Purified

Purification

Ion-exchange Purified

Limit Of Detection

Certified >95% pure using SDS-PAGE analysis. Low endotoxin <5 EU/mL @ 2mg/mL.

Concentration

2 mg/ml

Purity

>95%

Weight

Length

Full length

Buffer

PBS pH 7.4

Molecular Weight

13.33 kDa

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.

Additionnal Information

For corresponding PFFs, see catalog# SPR-459

References & Citations

1. Nishioka K., et al. (2010) Arch Neurol. 67(8): 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88(9): 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26(1): 32-42.

Shipping Conditions

Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.

Storage Conditions

-80ºC

Notes

For corresponding PFFs, see catalog# SPR-459

Protein Length

Full length

Background Reference 01

1. Nishioka K., et al. (2010) Arch Neurol. 67 (8) : 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88 (9) : 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26 (1) : 32-42.