Mefuparib
Mefuparib (CVL218) is a poly ADP-ribose polymerase (PARP) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.
Product Specifications
CAS Number
[1392502-82-7]
Product Name Alternative
CVL218
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mefuparib.html
Purity
99.77
Solubility
DMSO : 6.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC(F)=CC2=C1OC(C3=CC=C(CNC)C=C3)=C2)N
Molecular Formula
C17H15FN2O2
Molecular Weight
298.31
References & Citations
[1]Absorption, distribution, metabolism, and excretion of [14C]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15078790 1 Vial
Lentiviral human ZNF841 shRNA (UAS) - Lentiviral human ZNF841 shRNA (UAS, GFP) plasmid
Ask
View Details GTR15400871 1 Vial
Lentiviral human GALM sgRNA gene knockout kit - Lentiviral human GALM sgRNA gene knockout kit (plasmid)
Ask
View Details 
