Succinate Buffer (0.2 M, pH 5.5)

<strong>Succinate Buffer (0.2 M, pH 5.5)</strong>_x000D_ <strong>Catalog number:</strong> B2017985_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.2 M_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> N/A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Ukidve A, Rembert KB, Vanipenta R, Dorion P, Lafarguette P, McCoy T, Saluja A, Suryanarayanan R, Patke S. Succinate Buffer in Biologics Products: Real-world Formulation Considerations, Processing Risks and Mitigation Strategies J Pharm Sci. 2023 Jan;112(1):138-147._x000D_ 2: Kolhe P, Amend E, Singh SK. Impact of freezing on pH of buffered solutions and consequences for monoclonal antibody aggregation Biotechnol Prog. 2010 May-Jun;26(3):727-33._x000D_ 3: Treece TR, Tessman M, Pomeroy RS, Mayfield SP, Simkovsky R, Atsumi S. Fluctuating pH for efficient photomixotrophic succinate production Metab Eng. 2023 Sep;79:118-129._x000D_ 4: Sundaramurthi P, Suryanarayanan R. The effect of crystallizing and non-crystallizing cosolutes on succinate buffer crystallization and the consequent pH shift in frozen solutions Pharm Res. 2011 Feb;28(2):374-85._x000D_ 5: Gokarn YR, Kras E, Nodgaard C, Dharmavaram V, Fesinmeyer RM, Hultgen H, Brych S, Remmele RL Jr, Brems DN, Hershenson S. Self-buffering antibody formulations J Pharm Sci. 2008 Aug;97(8):3051-66._x000D_ 6: Karow AR, Bahrenburg S, Garidel P. Buffer capacity of biologics--from buffer salts to buffering by antibodies Biotechnol Prog. 2013 Mar-Apr;29(2):480-92._x000D_ 7: Garrigue P, Bodin-Hullin A, Balasse L, Fernandez S, Essamet W, Dignat-George F, Pacak K, Guillet B, Taïeb D. The Evolving Role of Succinate in Tumor Metabolism: An (18)F-FDG-Based Study J Nucl Med. 2017 Nov;58(11):1749-1755._x000D_ 8: Pluznick JL, Caplan MJ. Chemical and Physical Sensors in the Regulation of Renal Function Clin J Am Soc Nephrol. 2015 Sep 4;10(9):1626-35._x000D_ 9: Wichitnithad W, Nimmannit U, Wacharasindhu S, Rojsitthisak P. Synthesis, characterization and biological evaluation of succinate prodrugs of curcuminoids for colon cancer treatment Molecules. 2011 Feb 22;16(2):1888-900._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20302316">10: Sundaramurthi P, Shalaev E, Suryanarayanan R. Calorimetric and diffractometric evidence for the sequential crystallization of buffer components and the consequential pH swing in frozen solutions J Phys Chem B. 2010 Apr 15;114(14):4915-23. </a>_x000D_ _x000D_ <strong>Products Related to Succinate Buffer (0.2 M, pH 5.5) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>