Norbraylin
Norbraylin, a natural prenylated coumarin, is a PDE4D2 inhibitor with an IC50 value of 7.15 μM[1].
Product Specifications
CAS Number
[60796-64-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Phosphodiesterase (PDE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/norbraylin.html
Solubility
10 mM in DMSO
Smiles
CC1(C=CC2=C(C(O)=CC3=C2OC(C=C3)=O)O1)C
Molecular Formula
C14H12O4
Molecular Weight
244.24
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Lin Chen, et al. (P) / (M) -corinepalensin A, a pair of axially chiral prenylated bicoumarin enantiomers with a rare C-5C-5' linkage from the twigs of Coriaria nepalensis. Phytochemistry. 2018 May;149:140-145.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PDE4
Curated Selection
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