(5R) -5-Hydroxytriptolide

(5R) -5-Hydroxytriptolide is an extracted compound from Tripterygium, and shows lower cell cytotoxicity and higher immunosuppressive activity. (5R) -5-Hydroxytriptolide can be used for study of rheumatoid arthritis[1].

Product Specifications

CAS Number

[583028-68-6]

Product Name Alternative

PG 701; LLDT-8; 5α-Hydroxytriptolide

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/5r-5-hydroxytriptolide.html

Purity

99.67

Smiles

CC([C@@]12[C@H]([C@H]3[C@]4([C@@]5(C)CCC6=C(COC6=O)[C@]5(O)C[C@H]7[C@@]4(O7)[C@@H]2O)O3)O1)C

Molecular Formula

C20H24O7

Molecular Weight

376.40

References & Citations

[1]Guo S, et al. (5R) -5-Hydroxytriptolide (LLDT-8) induces substantial epigenetic mediated immune response network changes in fibroblast-like synoviocytes from rheumatoid arthritis patients. Sci Rep. 2019;9 (1) :11155. Published 2019 Aug 1.