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M-PEG4-azide

M-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. m-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[606130-90-9]

Product Name Alternative

13-Azido-2,5,8,11-tetraoxatridecane

UNSPSC

12352211

Hazard Statement

H302

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/m-peg4-azide.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

COCCOCCOCCOCCN=[N+]=[N-]

Molecular Formula

C9H19N3O4

Molecular Weight

233.26

Precautions

H302

References & Citations

[1]Belen Begines, et al. Synthesis of Reduction Sensitive Comb-Like Polyurethanes Using Click Chemistry. Journal of Polymer Science Part A: Polymer Chemistry, 2016, 54 (24), 3888-3900.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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