MBD

MBD (7- (p-Methoxybenzylamino) -4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule[1][2].

Product Specifications

CAS Number

[33984-50-8]

Product Name Alternative

7- (p-Methoxybenzylamino) -4-nitrobenz-2,1,3-oxadiazole

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mbd.html

Purity

98.93

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=[N+](C1=CC=C(NCC2=CC=C(OC)C=C2)C3=NON=C31)[O-]

Molecular Formula

C14H12N4O4

Molecular Weight

300.27

References & Citations

[1]Kenner RA, et al. A new fluorescent probe for protein and nucleoprotein conformation. Binding of 7- (p-methoxybenzylamino) -4-nitrobenzoxadiazole to bovine trypsinogen and bacterial ribosomes. Biochemistry. 1971;10 (24) :4433-4440.|[2]Kasahara Y, et al. Formation of a conformationally changed C1r, a subcomponent of the first component of human complement, as an intermediate of its autoactivation reaction. FEBS Lett. 1982;141 (1) :128-131.