Diphlorethohydroxycarmalol

Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities[1].

Product Specifications

CAS Number

[138529-04-1]

UNSPSC

12352005

Target

Glycosidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/diphlorethohydroxycarmalol.html

Purity

98.46

Solubility

H2O : 10 mg/mL (ultrasonic; warming)

Smiles

OC1=CC(O)=C(OC2=C(O)C(O)=C3OC4=CC(O)=C(OC5=CC(O)=CC(O)=C5)C(O)=C4OC3=C2)C(O)=C1

Molecular Formula

C24H16O13

Molecular Weight

512.38

References & Citations

[1]Soo-Jin Heo, et al. Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent alpha-glucosidase and alpha-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice. Eur J Pharmacol. 2009 Aug 1;615 (1-3) :252-6.