(E) -Methyl 4-coumarate
(E) -Methyl 4-coumarate (Methyl 4-hydroxycinnamate) is a phenolic compound and derivative of Cinnamic acid (HY-N0610A) . (E) -Methyl 4-coumarate can be found in several plants, such as the leaves of Allium cepa and Morinda citrifolia L. (E) -Methyl 4-coumarate, when combined with Carnosic acid (HY-N0644), induces Apoptosis. (E) -Methyl 4-coumarate inhibits GSK3β activity and modulates inflammatory cytokine levels (increasing IL-10 and decreasing IL-4) . (E) -Methyl 4-coumarate combined with Carnosic acid exhibits anticancer effects against acute myeloid leukemia. (E) -Methyl 4-coumarate ameliorates Plasmodium berghei NK65 infection[1][2].
Product Specifications
CAS Number
[19367-38-5]
Product Name Alternative
Methyl trans-p-coumarate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; GSK-3; Interleukin Related; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/e-methyl-4-coumarate.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)/C=C/C1=CC=C(O)C=C1
Molecular Formula
C10H10O3
Molecular Weight
178.19
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
GSK-3β; IL-10; IL-4
Available Sizes
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