Estradiol 3-glucuronide

Estradiol 3-glucuronide is an immunogen with antigenic properties. Estradiol 3-glucuronide induced antiserum in the rabbit possesses high afinity and specifcity to Estradiol 3-glucuronide. Estradiol 3-glucuronide is promising for research of radioimmunoassay[1][2].

Product Specifications

CAS Number

[15270-30-1]

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H315, H319, H335

Target

ATP-binding cassette (ABC) transporters; Endogenous Metabolite

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/estradiol-3-glucuronide.html

Purity

98.00

Solubility

H2O : 1 mg/mL (ultrasonic;warming)

Smiles

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)C(O)=O)C=C4CC3

Molecular Formula

C24H32O8

Molecular Weight

448.51

Precautions

H302+H312+H332, H315, H319, H335

References & Citations

[1]Nambara T, et al. A direct radioimmunoassay of estradiol 3-glucuronide using specific antiserum. Chem Pharm Bull (Tokyo) . 1983 Oct;31 (10) :3583-8. |[2]Gerk PM, et al. Estradiol 3-glucuronide is transported by the multidrug resistance-associated protein 2 but does not activate the allosteric site bound by estradiol 17-glucuronide. Drug Metab Dispos. 2004 Oct;32 (10) :1139-45.