BMS-986124
Product Specifications
UNSPSC Description
BMS-986124 is a μ-opioid receptor silent allosteric modulator (μ-SAMs). BMS-986124 antagonizes positive allosteric modulator effect of BMS-986122 (µ-OR PAM)[1].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bms-986124.html
Smiles
O=S(C1=CC=C(C=C1)Cl)(N2CCSC2C3=CC=C(C=C3OC)Br)=O
Molecular Weight
448.78
References & Citations
[1]Burford NT, et al. Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10830-5.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118416/BMS-986124-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118416/
Clinical Information
No Development Reported
CAS Number
1447968-71-9
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